Prescription Clinical MonographPrescription Therapeutic Agent
Verified Evidence Sources: openFDA & NLM MedlinePlus

Acitretin

Comprehensive clinical interaction and dietary monograph for Acitretin (Acitretin).

Generic Active Chemical: Acitretin
Brand Formulations:Soriatane

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients
1 Flagged Foods
HIGH

Alcoholic Beverages (Beer, Wine, Spirits)

NutriDive Kitchen Food Biochemical Ontology & openFDA
Bioactive Compound:Ethanol
Biological Target:GABA-A Receptors, Hepatic CYP2E1 & Gluconeogenesis
Clinical Mechanism:

Multiplies respiratory depression and profound sedation with opioids and sedatives; blocks hepatic lactate uptake with metformin (lactic acidosis); triggers acute disulfiram-like vomiting and tachycardia with metronidazole; and accelerates dose-dumping in extended-release capsules.

Patient Actionable Rule:Completely abstain from alcohol while taking metronidazole, cephalosporins, prescription sedatives, or empty-stomach metformin.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions
0 Warning Classes
No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations
0 Monitored
No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols
0 Protocols

Frequently Researched Drug-Substance Combinations

Explore pairwise interaction dossiers and laboratory safety analyses
Multi-Substance Interactive Radar

Taking Acitretin alongside daily coffee, supplements, or other medications?

Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.

Launch SafeStack Radar with Acitretin→
Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.