Amlodipine and Benazepril
Comprehensive clinical interaction and dietary monograph for Amlodipine and Benazepril (Amlodipine and Benazepril).
Kitchen Food, Drink & Dietary Conflicts
Biochemical interactions with common foods, beverages & cooking ingredientsTalk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.
Grapefruit / Pomelo (Citrus paradisi / Citrus maxima)
Destroys enterocyte CYP3A4 enzymes, collapsing first-pass drug metabolism and causing up to 12-fold spikes in bioavailability for oral CYP3A4 substrates (statins, calcium channel blockers, immunosuppressants, PDE5 inhibitors).
Potassium-Enriched Salt Substitutes (Low-Sodium Table Salt)
Provides 500-1400 mg potassium per 1/4 teaspoon. When renal potassium excretion is suppressed by ACE inhibitors, ARBs, or aldosterone antagonists (spironolactone), acute severe hyperkalemia (>6.5 mEq/L) can trigger sudden flaccid paralysis and fatal ventricular fibrillation.
Prescription & OTC Drug Interactions (DDI)
Documented pharmacological conflicts & contraindicated co-prescriptionsDietary Supplements, Herbs & Minerals (DNI)
Interactions with over-the-counter vitamins, minerals, and herbal preparationsPotassium Supplements (Potassium Chloride, Gluconate, Citrate)
Direct renin inhibition suppresses downstream aldosterone secretion, preventing physiological urinary potassium excretion. Exogenous potassium supplements directly provoke dangerous serum hyperkalemia.
Chronotherapy & Meal Administration Protocols
Optimal absorption, meal-timing rules & GI tolerability protocolsFrequently Researched Drug-Substance Combinations
Explore pairwise interaction dossiers and laboratory safety analysesAmlodipine and Benazepril and Potassium
Pairwise Clinical Analysis & Safety RatingAmlodipine and Benazepril and Salt-substitute
Pairwise Clinical Analysis & Safety RatingAmlodipine and Benazepril and Grapefruit / Pomelo
Pairwise Clinical Analysis & Safety RatingAmlodipine and Benazepril and Potassium Salt Substitutes
Pairwise Clinical Analysis & Safety RatingTaking Amlodipine and Benazepril alongside daily coffee, supplements, or other medications?
Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.
Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.