Prescription Clinical MonographPrescription Therapeutic Agent
Verified Evidence Sources: openFDA & NLM MedlinePlus

Clarithromycin

Comprehensive clinical interaction and dietary monograph for Clarithromycin (Clarithromycin).

Generic Active Chemical: Clarithromycin
Brand Formulations:Biaxin Filmtab¶Biaxin Granules¶Biaxin XL Filmtab¶Biaxin XL Pac¶

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients
1 Flagged Foods
CRITICAL

Potassium-Enriched Salt Substitutes (NoSalt, Nu-Salt)

NLM MedlinePlus Dietary Warning & openFDA
Bioactive Compound:Potassium Chloride (KCl)
Biological Target:Renal Cortical Collecting Duct Electrophysiology
Clinical Mechanism:

Exogenous potassium chloride loads cannot be cleared efficiently when RAAS or renal filtration is modified, risking acute lethal hyperkalemia (>6.5 mEq/L) and ventricular arrhythmias.

Patient Actionable Rule:Strictly avoid low-sodium seasonings containing potassium chloride without explicit physician approval and laboratory electrolyte monitoring.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions
0 Warning Classes
No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations
0 Monitored
No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols
1 Protocols
MEALMealtime Administration

Take the extended-release tablet with food every 24 hours (once a day) for 7 to 14 days.

Rationale: Food enhances bioavailability, prevents gastric mucosal irritation, or stabilizes peak-to-trough pharmacokinetic variations.

Frequently Researched Drug-Substance Combinations

Explore pairwise interaction dossiers and laboratory safety analyses
Multi-Substance Interactive Radar

Taking Clarithromycin alongside daily coffee, supplements, or other medications?

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Launch SafeStack Radar with Clarithromycin→
Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.