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Verified Evidence Sources: openFDA & NLM MedlinePlus

Ethinyl Estradiol and Levonorgestrel (Oral Contraceptives)

Comprehensive clinical interaction and dietary monograph for Ethinyl Estradiol and Levonorgestrel (Oral Contraceptives) (Ethinyl Estradiol and Levonorgestrel (Oral Contraceptives)).

Generic Active Chemical: Ethinyl Estradiol and Levonorgestrel (Oral Contraceptives)
Brand Formulations:AubraAfirmelleAlesse¶AltaveraAshynaAvianeAyunaBalcoltraCerinta¶ChatealDayseeChabelinaDolishaleElifemme¶EnpresseFalminaFayosim¶IntrovaleJaimiessKurveloLessinaLevlite¶LevoraLo SimpesseLybel¶MarlissaMinzoyaMyzilraNordette¶Orsythia¶PortiaQuartetteQuasenseSeasonaleSeasoniqueSetlakinSimpesseSylevia¶Tri-Phasil¶Tri-VoraTyblumeVienva
Quick Jump:Kitchen Foods (1)Drug Red Flags (0)Supplements & Herbs (0)Administration Timing (0)

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients
1 Flagged Foods
HIGH

Green Tea, Black Tea & Matcha (Tannins & OATP Inhibitors)

NutriDive Kitchen Food Biochemical Ontology & openFDA
Bioactive Compound:Polyphenolic Tannins & Catechins (EGCG)
Biological Target:Ionic Iron Transporters & OATP1A2 / OATP2B1
Clinical Mechanism:

Tannins form insoluble macromolecular iron-tannate precipitates, dropping non-heme iron absorption by up to 80%. Catechins additionally inhibit intestinal OATP uptake transporters, drastically reducing bioavailability of beta-blockers (atenolol) and allergy medications (fexofenadine).

Patient Actionable Rule:Do not take oral iron supplements with tea; drink tea between meals at least 2 hours apart. If taking fexofenadine or nadolol, avoid green tea within 4 hours.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions
0 Warning Classes
No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations
0 Monitored
No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols
0 Protocols
Multi-Substance Interactive Radar

Taking Ethinyl Estradiol and Levonorgestrel (Oral Contraceptives) alongside daily coffee, supplements, or other medications?

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Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.

View Original NLM MedlinePlus Monograph·Clinical & Legal Disclaimers