Guaifenesin

Comprehensive clinical interaction and dietary monograph for Guaifenesin (Guaifenesin).

Generic Active Chemical: Guaifenesin

Brand Formulations:Adult TussinAir PowerBronchorilChest CongestionChildrens MucinexChildrens Mucus ReliefCough OutDiabetic Siltussin DAS-NaDiabetic Tussin ExpectorantDiabetic Tussin Mucus ReliefEqualine TussinEquate TussinGood Neighbor Pharmacy TussinGood Sense TussinGuiatussIophen NRKids-EEZELeader Adult TussinLeader Mucus ReliefLiqufrutaLittle Remedies Little Colds Mucus Relief Expectorant Melt AwaysMucaPlexMucinexMucinex for KidsMucus ReliefMucus Relief ChestORGAN-I NRPremier Value Chest Congestion ReliefQ-TussinRefenesen Chest Congestion ReliefRobitussin Chest CongestionScot-Tussin Expectorant SF CoughSelectHealth Tussin DMSiltussin DASSiltussin SASmart Sense TussinSunmark TussinTopcare Mucus ReliefTopcare TussinTussinTussin ChestTussin Chest CongestionTussin OriginalUp and Up Childrens Mucus ReliefVicks DayQuilWal TussinAdult Tussin DM (containing Dextromethorphan, Guaifenesin)Aldex (containing Guaifenesin, Pseudoephedrine)Biocotron (containing Dextromethorphan, Guaifenesin)Biospec (containing Dextromethorphan, Guaifenesin)Bisolvine (containing Dextromethorphan, Guaifenesin)Care One Chest Congestion Relief (containing Dextromethorphan, Guaifenesin)Certuss (containing Chlophedianol, Guaifenesin)Cheratussin AC (containing Codeine, Guaifenesin)chest congestion (containing Dextromethorphan, Guaifenesin)Childrens Mucus Relief (containing Dextromethorphan, Guaifenesin)Childrens Mucus Relief Cherry (containing Dextromethorphan, Guaifenesin)Childrens Mucus Relief Cough Cherry (containing Dextromethorphan, Guaifenesin)Childrens Relief Cherry (containing Dextromethorphan, Guaifenesin)Chlo Tuss (containing Chlophedianol, Guaifenesin)Codar (containing Codeine, Guaifenesin)Cough (containing Dextromethorphan, Guaifenesin)Cough Syrup (containing Dextromethorphan, Guaifenesin)CounterAct (containing Dextromethorphan, Guaifenesin)CVS Chest Congestion Relief (containing Dextromethorphan, Guaifenesin)Dex-Tuss (containing Codeine, Guaifenesin)DG Health Childrens Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)DG Health Tussin DM (containing Dextromethorphan, Guaifenesin)Diabetic Tussin DM (containing Dextromethorphan, Guaifenesin)Diabetic Tussin DM Maximum Strength (containing Dextromethorphan, Guaifenesin)Donatussin Drops (containing Guaifenesin, Phenylephrine)Double Tussin Intense Cough Reliever (containing Dextromethorphan, Guaifenesin)Equaline Adult Tussin (containing Dextromethorphan, Guaifenesin)Equaline Tussin Cough and Chest Congestion (containing Dextromethorphan, Guaifenesin)Equate Tussin DM (containing Dextromethorphan, Guaifenesin)Expectorant Plus Cough Relief (containing Dextromethorphan, Guaifenesin)FormuCare Cough Syrup DM (containing Dextromethorphan, Guaifenesin)Freds Chest Congestion Relief (containing Dextromethorphan, Guaifenesin)Good Neighbor Pharmacy Adult Tussin (containing Dextromethorphan, Guaifenesin)Good Neighbor Pharmacy Tussin DM (containing Dextromethorphan, Guaifenesin)Good Neighbor Pharmacy Tussin DM Max (containing Dextromethorphan, Guaifenesin)Good Sense Childrens Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)Good Sense tussin (containing Dextromethorphan, Guaifenesin)Good Sense Tussin DM (containing Dextromethorphan, Guaifenesin)Guaiasorb DM (containing Dextromethorphan, Guaifenesin)Guaiatussin AC (containing Codeine, Guaifenesin)Guiatuss DM (containing Dextromethorphan, Guaifenesin)Healthy Accents Tussin DM (containing Dextromethorphan, Guaifenesin)Iophen C NR (containing Codeine, Guaifenesin)Iophen DM NR (containing Dextromethorphan, Guaifenesin)Leader Adult Tussin DM (containing Dextromethorphan, Guaifenesin)Leader Childrens Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)Leader Intense Cough Reliever (containing Dextromethorphan, Guaifenesin)Leader Tussin DM Max (containing Dextromethorphan, Guaifenesin)Lusair (containing Guaifenesin, Phenylephrine)Mucinex Fast-Max (containing Dextromethorphan, Guaifenesin)Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)Mucus Relief DM (containing Dextromethorphan, Guaifenesin)Nature Fusion (containing Dextromethorphan, Guaifenesin)PediaCare Childrens Cough and Congestion (containing Dextromethorphan, Guaifenesin)Premier Value Chest Congestion and Cough Relief (containing Dextromethorphan, Guaifenesin)Primatene (containing Ephedrine, Guaifenesin)Q Tussin DM (containing Dextromethorphan, Guaifenesin)RelCof-C (containing Codeine, Guaifenesin)Robafen DM Max (containing Dextromethorphan, Guaifenesin)Robitussin Cough and Chest Congestion DM (containing Dextromethorphan, Guaifenesin)Safetussin (containing Dextromethorphan, Guaifenesin)Scot-Tussin Senior SF DMExp (containing Dextromethorphan, Guaifenesin)Smart Sense Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)Smart Sense tussin dm max (containing Dextromethorphan, Guaifenesin)Sun Mark Mucus Relief Cough (containing Dextromethorphan, Guaifenesin)Sun Mark Tussin DM (containing Dextromethorphan, Guaifenesin)Sunmark Tussin DM (containing Dextromethorphan, Guaifenesin)Topcare Mucus Relief (containing Dextromethorphan, Guaifenesin)Topcare tussin dm (containing Dextromethorphan, Guaifenesin)Topcare Tussin DM Max (containing Dextromethorphan, Guaifenesin)Tussin Cough DM (containing Dextromethorphan, Guaifenesin)Tussin DM (containing Dextromethorphan, Guaifenesin)Up and Up Adult Cough Formula DM (containing Dextromethorphan, Guaifenesin)Up and Up Childrens Mucus Relief and Cough (containing Dextromethorphan, Guaifenesin)Vanacof (containing Chlophedianol, Guaifenesin)Vicks DayQuil (containing Dextromethorphan, Guaifenesin)Wal Tussin DM (containing Dextromethorphan, Guaifenesin)Z-Cof 1 (containing dextromethorphan and Guaifenesin, Pseudoephedrine)Zicam (containing acetaminophen and Dextromethorphan, Guaifenesin)Zodryl DEC (containing pseudoephedrine and Codeine, Guaifenesin)Zyncof (containing Dextromethorphan, Guaifenesin)

Quick Jump:Kitchen Foods (0)Drug Red Flags (0)Supplements & Herbs (0)Administration Timing (1)

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients

0 Flagged Foods

Official Patient Dietary Instruction (NLM MedlinePlus)

Drink plenty of fluids while you are taking this medication. Unless your doctor tells you otherwise, continue your normal diet.

Unless your physician explicitly directs otherwise, continue your normal balanced diet while taking this medication. Maintain consistent hydration and meal intervals.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions

0 Warning Classes

No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations

0 Monitored

No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols

1 Protocols

MEALAdministration Rule

Swallow the extended-release tablets whole with a full glass of water.

Rationale: Promotes optimal mucosal absorption and consistent therapeutic plasma levels.

Multi-Substance Interactive Radar

Taking Guaifenesin alongside daily coffee, supplements, or other medications?

Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.

Launch SafeStack Radar with Guaifenesin→

Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.

View Original NLM MedlinePlus Monograph·Clinical & Legal Disclaimers