Mesalamine Rectal

Comprehensive clinical interaction and dietary monograph for Mesalamine Rectal (Mesalamine Rectal).

Generic Active Chemical: Mesalamine Rectal

Brand Formulations:CanasaRowasasfRowasa

Quick Jump:Kitchen Foods (1)Drug Red Flags (0)Supplements & Herbs (0)Administration Timing (0)

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients

1 Flagged Foods

HIGH

Aged Cheese, Cured Meats & Fermented Foods (High-Tyramine)

NutriDive Kitchen Food Biochemical Ontology & openFDA

Bioactive Compound:Tyramine (Decarboxylated Tyrosine)

Biological Target:Presynaptic Vesicular Monoamine Transporter (VMAT)

Clinical Mechanism:

Under monoamine oxidase (MAO) inhibition, ingested dietary tyramine escapes intestinal deamination, enters systemic circulation, and displaces massive catecholamine stores, triggering acute fatal hypertensive crises, intracranial hemorrhage, and cardiac arrest.

Patient Actionable Rule:Strict dietary tyramine restriction is required starting on the first day of MAOI therapy and continuing for 14 days after discontinuation to allow MAO enzyme regeneration.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions

0 Warning Classes

No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations

0 Monitored

No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols

0 Protocols

Multi-Substance Interactive Radar

Taking Mesalamine Rectal alongside daily coffee, supplements, or other medications?

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Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.

View Original NLM MedlinePlus Monograph·Clinical & Legal Disclaimers