Prescription Clinical MonographPrescription Therapeutic Agent
Verified Evidence Sources: openFDA & NLM MedlinePlus
Phenylephrine
Comprehensive clinical interaction and dietary monograph for Phenylephrine (Phenylephrine).
Generic Active Chemical: Phenylephrine
Brand Formulations:Children's Sudafed PE Nasal DecongestantLusonal§PediaCare Children's DecongestantSudafed PE CongestionSuphedrin PEA Tan 12x Suspension (containing Phenylephrine, Pyrilamine)§AccuHist (containing Chlorpheniramine, Phenylephrine)AccuHist PDX (containing Brompheniramine, Dextromethorphan, Phenylephrine)Actifed Cold and Allergy (containing Chlorpheniramine, Phenylephrine)Advil Congestion Relief (containing Ibuprofen, Phenylephrine)Aerohist Plus (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Aerokid (containing Chlorpheniramine, Methscopolamine, Phenylephrine)¶Ah Chew (containing Chlorpheniramine, Phenylephrine)§Ah Chew Ultra (containing Chlorpheniramine, Phenylephrine, Methscopolamine)§Alahist DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)Alahist LQ (containing Diphenhydramine, Phenylephrine)Albatussin NN (containing Dextromethorphan, Phenylephrine, Potassium Guaiacolsulfonate, Pyrilamine)§Aldex CT (containing Diphenhydramine, Phenylephrine)Aldex D (containing Phenylephrine, Pyrilamine)Alka-Seltzer Plus Cold and Cough Formula (containing Aspirin, Chlorpheniramine, Dextromethorphan, Phenylephrine)Alka-Seltzer Plus Day and Night Cold Formulas (containing Aspirin, Dextromethorphan, Phenylephrine)Alka-Seltzer Plus Day Non-Drowsy Cold Formula (containing Acetaminophen, Dextromethorphan, Phenylephrine)Alka-Seltzer Plus Fast Powder Packs (containing Acetaminophen, Chlorpheniramine, Phenylephrine)Alka-Seltzer Plus Flu Formula (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)Alka-Seltzer Plus Night Cold Formula (containing Aspirin, Dextromethorphan, Doxylamine, Phenylephrine)Alka-Seltzer Plus Sinus Formula (containing Aspirin, Phenylephrine)Alka-Seltzer Plus Sparkling Original Cold Formula (containing Aspirin, Chlorpheniramine, Phenylephrine)Allerest PE (containing Chlorpheniramine, Phenylephrine)Allergy DN PE (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§AlleRx (containing Chlorpheniramine, Phenylephrine)§Amerituss AD (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)¶Aquatab C (containing Carbetapentane, Dextromethorphan, Guaifenesin, Phenylephrine)§Aridex (containing Carbetapentane, Carbinoxamine, Phenylephrine)¶B Vex D (containing Brompheniramine, Phenylephrine)§Balacall DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)¶Baltussin HC (containing Chlorpheniramine, Hydrocodone, Phenylephrine)¶Benadryl-D Allergy Plus Sinus (containing Diphenhydramine, Phenylephrine)Betatan (containing Brompheniramine, Carbetapentane, Phenylephrine)§Biotuss (containing Dextromethorphan, Guaifenesin, Phenylephrine)§BPM PE DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)§Bromaphedrine D (containing Brompheniramine, Phenylephrine)§Bromhist PDX (containing Brompheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§Bromtuss DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)§Broncopectol (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)¶Bronkids (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Brontuss DX (containing Dextromethorphan, Guaifenesin, Phenylephrine)Brontuss SF (containing Dextromethorphan, Guaifenesin, Phenylephrine)Brotapp PE-DM Cough and Cold (containing Brompheniramine, Dextromethorphan, Phenylephrine)Brovex D (containing Brompheniramine, Phenylephrine)§Brovex PEB (containing Brompheniramine, Phenylephrine)Brovex PEB DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)C Phen (containing Chlorpheniramine, Phenylephrine)§C Phen DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Cardec DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)Centergy (containing Chlorpheniramine, Phenylephrine)§Centergy DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Centussin DHC (containing Brompheniramine, Dihydrocodeine, Phenylephrine)§Ceron (containing Chlorpheniramine, Phenylephrine)Ceron DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Cerose DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)¶Children's Dimetapp Cold and Allergy (containing Brompheniramine, Phenylephrine)Children's Dimetapp Cold and Cough (containing Brompheniramine, Dextromethorphan, Phenylephrine)Children's Dimetapp Multisymptom Cold and Flu (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)Children's Dimetapp Nighttime Cold and Congestion (containing Diphenhydramine, Phenylephrine)Children's Mucinex Multi-Symptom Cold (containing Dextromethorphan, Guaifenesin, Phenylephrine)Children's Mucinex Stuffy Nose and Cold (containing Guaifenesin, Phenylephrine)Children's Robitussin Cough and Cold CF (containing Dextromethorphan, Guaifenesin, Phenylephrine)Children's Sudafed PE Cold and Cough (containing Dextromethorphan, Phenylephrine)Chlordex GP (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§Codal-DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)¶Codimal DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)¶Comtrex Cold and Cough Day/Night (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)Comtrex Cold and Cough Non-Drowsy (containing Acetaminophen, Dextromethorphan, Phenylephrine)Contac Cold and Flu (containing Acetaminophen, Phenylephrine)Corfen DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)Coryza DM (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)§Dallergy Drops (containing Chlorpheniramine, Phenylephrine)Dallergy PE (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Decon E (containing Guaifenesin, Phenylephrine)§Decon G (containing Brompheniramine, Guaifenesin, Phenylephrine)§Deconex (containing Guaifenesin, Phenylephrine)¶Dehistine (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Despec (containing Guaifenesin, Phenylephrine)Despec NR (containing Dextromethorphan, Guaifenesin, Phenylephrine)Donatuss DC (containing Dihydrocodeine, Guaifenesin, Phenylephrine)§Donatussin (containing Guaifenesin, Phenylephrine)Donatussin DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)Donatussin MAX (containing Carbinoxamine, Hydrocodone, Phenylephrine)¶Dristan Cold Multi-Symptom Formula (containing Acetaminophen, Chlorpheniramine, Phenylephrine)Dryphen (containing Acetaminophen, Chlorpheniramine, Phenylephrine)¶Duravent-DPB (containing Brompheniramine, Dextromethorphan, Phenylephrine)§Dynatuss EX (containing Dextromethorphan, Guaifenesin, Phenylephrine)§EndaCof-DH (containing Brompheniramine, Dihydrocodeine, Phenylephrine)EndaCof-Plus (containing Dexchlorpheniramine, Hydrocodone, Phenylephrine)¶Endacon DM (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Endal CD (containing Chlorpheniramine, Codeine, Phenylephrine)Endal HD (containing Diphenhydramine, Phenylephrine)§Entex LA (containing Guaifenesin, Phenylephrine)§Entex LQ (containing Guaifenesin, Phenylephrine)Excedrin Sinus Headache (containing Acetaminophen, Phenylephrine)Execof (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Extendryl (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Genetuss 2 (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Gentex LQ (containing Carbetapentane, Guaifenesin, Phenylephrine)§Giltuss (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Guiatex PE (containing Guaifenesin, Phenylephrine)§Histadec (containing Chlorpheniramine, Phenylephrine)¶Histinex HC (containing Chlorpheniramine, Hydrocodone, Phenylephrine)¶Hycomine Compound (containing Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine)¶J-Max (containing Guaifenesin, Phenylephrine)J-Tan D PD (containing Brompheniramine, Phenylephrine)§Lartus (containing Dextromethorphan, Guaifenesin, Phelyephrine)§Levall (containing Carbetapentane, Guaifenesin, Phenylephrine)§Liquibid D-R (containing Guaifenesin, Phenylephrine)Liquibid PD-R (containing Guaifenesin, Phenylephrine)Lohist-DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)§LoHist-PEB (containing Brompheniramine, Phenylephrine)LoHist-PEB-DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)Lortuss HC (containing Hydrocodone, Phenylephrine)¶Lusair (containing Guaifenesin, Phenylephrine)¶Lusonex (containing Guaifenesin, Phenylephrine)§Maxiphen (containing Guaifenesin, Phenylephrine)§Maxiphen ADT (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Mintuss DR (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Montephen (containing Guaifenesin, Phenylephrine)§MyHist DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§Naldex (containing Dexchlorpheniramine, Phenylephrine)§Nariz (containing Guaifenesin, Phenylephrine)¶Nasohist (containing Chlorpheniramine, Phenylephrine)Nasohist DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)Neo DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§NoHist (containing Chlorpheniramine, Phenylephrine)§NoHist-DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)NoHist-LQ (containing Chlorpheniramine, Phenylephrine)Norel DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Norel SR (containing Acetaminophen, Chlorpheniramine, Phenylephrine, Phenyltoloxamine)§Notuss-PE (containing Codeine, Phenylephrine)Novahistine (containing Chlorpheniramine, Phenylephrine)¶Omnihist II LA (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Oratuss (containing Carbetapentane, Guaifenesin, Phenylephrine)§PediaCare Children's Allergy and Cold (containing Diphenhydramine, Phenylephrine)PediaCare Children's Fever Reducer Plus Flu (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)PediaCare Children's Fever Reducer Plus Multi-Symptom Cold (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)PediaCare Children's Multi-Symptom Cold (containing Dextromethorphan, Phenylephrine)Phenabid (containing Chlorpheniramine, Phenylephrine)§Phencarb GG (containing Carbetapentane, Guaifenesin, Phenylephrine)§Phenergan VC (containing Phenylephrine, Promethazine)¶Poly Hist DHC (containing Dihydrocodeine, Phenylephrine, Pyrilamine)§Poly Hist DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§Poly Hist PD (containing Chlorpheniramine, Phenylephrine, Pyrilamine)§Polytan D (containing Dexbrompheniramine, Phenylephrine)§Polytan DM (containing Dexbrompheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)§Poly-Tussin AC (containing Brompheniramine, Codeine, Phenylephrine)Poly-Tussin DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)Poly-Tussin EX (containing Dihydrocodeine, Guaifenesin, Phenylephrine)§Prolex PD (containing Guaifenesin, Phenylephrine)§Prometh VC (containing Phenylephrine, Promethazine)Promethazine VC (containing Phenylephrine, Promethazine)Protid (containing Acetaminophen, Chlorpheniramine, Phenylephrine)¶Pyrlex PD (containing Phenylephrine, Pyrilamine)§Quartuss (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)§Quartuss DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Quintex (containing Guaifenesin, Phenylephrine)§Re Allergy AM/PM (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Re Drylex (containing Dexchlorpheniramine, Methscopolamine, Phenylephrine)§Redur PCM (containing Chlorpheniramine, Phenylephrine)§Relcof PE (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§RemeHist DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§RemeTussin DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Rescon (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Respa PE (containing Guaifenesin, Phenylephrine)§RespaHist II (containing Brompheniramine, Phenylephrine)§Resperal (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)¶Rhinabid (containing Brompheniramine, Phenylephrine)§RhinaHist (containing Dexchlorpheniramine, Phenylephrine)¶Rinate (containing Chlorpheniramine, Phenylephrine)¶Robitussin Cough and Cold CF (containing Dextromethorphan, Guaifenesin, Phenylephrine)Robitussin Night Time Cough and Cold (containing Diphenhydramine, Phenylephrine)Robitussin Night Time Cough, Cold, and Flu (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)Rondex (containing Chlorpheniramine, Phenylephrine)¶R-Tanna (containing Chlorpheniramine, Phenylephrine)§Ryna (containing Phenylephrine, Pyrilamine)§Rynatan (containing Chlorpheniramine, Phenylephrine)§Rynatuss (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)§Ry-Tuss (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)§ScopoHist (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Seradex (containing Brompheniramine, Phenylephrine)§Sildec PE DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Sine-Off Cough/Cold (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)Sine-Off Non-Drowsy (containing Acetaminophen, Phenylephrine)Sine-Off Severe Cold (containing Acetaminophen, Guaifenesin, Phenylephrine)Sine-Off Sinus/Cold (containing Acetaminophen, Chlorpheniramine, Phenylephrine)Sinutuss DM (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Sinuvent PE (containing Guaifenesin, Phenylephrine)§Sitrex (containing Guaifenesin, Phenylephrine)§Sonahist (containing Chlorpheniramine, Phenylephrine)§Sonahist DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Statuss DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Sudafed PE Cold/Cough (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)Sudafed PE Day/Night Cold (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine)Sudafed PE Day/Night Congestion (containing Diphenhydramine, Phenylephrine)Sudafed PE Non-Drying Sinus (containing Guaifenesin, Phenylephrine)Sudafed PE Pressure/Pain (containing Acetaminophen, Phenylephrine)Sudafed PE Severe Cold (containing Acetaminophen, Diphenhydramine, Phenylephrine)Sudafed PE Sinus/Allergy (containing Chlorpheniramine, Phenylephrine)Sudafed PE Triple Action (containing Acetaminophen, Guaifenesin, Phenylephrine)Sympak PDX (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Tanabid (containing Brompheniramine, Phenylephrine)§Tannate (containing Carbetapentane, Phenylephrine, Pyrilamine)§Theraflu Cold and Cough (containing Dextromethorphan, Pheniramine, Phenylephrine)Theraflu Cold and Sore Throat (containing Acetaminophen, Pheniramine, Phenylephrine)Theraflu Daytime Severe Cold and Cough (containing Acetaminophen, Dextromethorphan, Phenylephrine)Theraflu Flu and Sore Throat (containing Acetaminophen, Pheniramine, Phenylephrine)Theraflu Nighttime Severe Cold and Cough (containing Acetaminophen, Diphenhydramine, Phenylephrine)Theraflu Sinus and Cold (containing Acetaminophen, Pheniramine, Phenylephrine)Trexbrom (containing Brompheniramine, Carbetapentane, Phenylephrine)§Triall (containing Chlorpheniramine, Methscopolamine, Phenylephrine)§Triaminic Chest and Nasal Congestion (containing Guaifenesin, Phenylephrine)Triaminic Cold and Allergy (containing Chlorpheniramine, Phenylephrine)Triaminic Day Time Cold and Cough (containing Dextromethorphan, Phenylephrine)Triaminic Night Time Cold and Cough (containing Diphenhydramine, Phenylephrine)Triplex DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§Trital DM (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)§Tritan (containing Chlorpheniramine, Phenylephrine, Pyrilamine)§Trituss (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Tusdec DM (containing Brompheniramine, Dextromethorphan, Phenylephrine)§Tussafed EX (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Tussbid (containing Guaifenesin, Phenylephrine)§Tussi 12D (containing Carbetapentane, Phenylephrine, Pyrilamine)§Tussi Pres (containing Dextromethorphan, Guaifenesin, Phenylephrine)Tussidex (containing Dextromethorphan, Guaifenesin, Phenylephrine)§Tussin CF (containing Dextromethorphan, Guaifenesin, Phenylephrine)Tylenol Allergy Multi-Symptom (containing Acetaminophen, Chlorpheniramine, Phenylephrine)Tylenol Allergy Multi-Symptom Nighttime (containing Acetaminophen, Diphenhydramine, Phenylephrine)Tylenol Cold and Flu Severe (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)Tylenol Cold Multi-Symptom Nighttime (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)Tylenol Cold Multi-Symptom Severe (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)Tylenol Sinus Congestion and Pain Daytime (containing Acetaminophen, Phenylephrine)Tylenol Sinus Congestion and Pain Nighttime (containing Acetaminophen, Chlorpheniramine, Phenylephrine)Tylenol Sinus Congestion and Pain Severe (containing Acetaminophen, Guaifenesin, Phenylephrine)V Tann (containing Phenylephrine, Pyrilamine)§Vanacof CD (containing Dexchlorpheniramine, Phenylephrine)§Vazobid (containing Brompheniramine, Phenylephrine)§Vazotan (containing Brompheniramine, Carbetapentane, Phenylephrine)¶V-Cof (containing Brompheniramine, Carbetapentane, Phenylephrine)§V-Hist (containing Brompheniramine, Phenylephrine)§Vicks DayQuil Cold and Flu Relief (containing Acetaminophen, Dextromethorphan, Phenylephrine)Vicks DayQuil Cold and Flu Symptom Relief Plus Vitamin C (containing Acetaminophen, Dextromethorphan, Phenylephrine)Vicks DayQuil Sinex Daytime Sinus Relief (containing Acetaminophen, Phenylephrine)Vicks Formula 44 Custom Care Congestion (containing Dextromethorphan, Phenylephrine)Vicks NyQuil Sinex Nighttime Sinus Relief (containing Acetaminophen, Doxylamine, Phenylephrine)Vicks VapoSyrup Severe Congestion (containing Guaifenesin, Phenylephrine)Viratan DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§Viravan DM (containing Dextromethorphan, Phenylephrine, Pyrilamine)§Viravan T (containing Phenylephrine, Pyrilamine)§Visonex (containing Guaifenesin, Phenylephrine)§Wellbid D (containing Guaifenesin, Phenylephrine)§Y-Cof DMX (containing Brompheniramine, Dextromethorphan, Phenylephrine)Z-Dex (containing Dextromethorphan, Guaifenesin, Phenylephrine)Zotex (containing Dextromethorphan, Guaifenesin, Phenylephrine)§
Kitchen Food, Drink & Dietary Conflicts
Biochemical interactions with common foods, beverages & cooking ingredientsHIGH
NutriDive Kitchen Food Biochemical Ontology & openFDACoffee & High-Caffeine Beverages (Espresso, Energy Drinks)
Bioactive Compound:1,3,7-Trimethylxanthine (Caffeine)
Biological Target:Cytochrome P450 1A2 (CYP1A2) & Adenosine A1/A2A Receptors
Clinical Mechanism:
Ciprofloxacin, fluvoxamine, and oral contraceptives inhibit CYP1A2, reducing caffeine clearance by 30-80% and precipitating palpitations, panic, and severe tremors. Caffeine also accelerates gastric motility, impairing bisphosphonate and thyroid absorption.
Patient Actionable Rule:Take thyroid hormones and bisphosphonates with pure plain water only. Moderate or avoid concentrated caffeine during ciprofloxacin therapy.
CRITICAL
NLM MedlinePlus Dietary Warning & openFDAPotassium-Enriched Salt Substitutes (NoSalt, Nu-Salt)
Bioactive Compound:Potassium Chloride (KCl)
Biological Target:Renal Cortical Collecting Duct Electrophysiology
Clinical Mechanism:
Exogenous potassium chloride loads cannot be cleared efficiently when RAAS or renal filtration is modified, risking acute lethal hyperkalemia (>6.5 mEq/L) and ventricular arrhythmias.
Patient Actionable Rule:Strictly avoid low-sodium seasonings containing potassium chloride without explicit physician approval and laboratory electrolyte monitoring.
Prescription & OTC Drug Interactions (DDI)
Documented pharmacological conflicts & contraindicated co-prescriptionsHIGH RISK
openFDA SPL Section 7 (Drug Interactions)NSAIDs (Ibuprofen, Naproxen) & Non-Cardioprotective Analgesics
Mechanism: Inhibition of renal vasodilatory prostaglandins (PGI2, PGE2) causes afferent arteriolar vasoconstriction, blunts blood pressure control, and increases risk of acute kidney injury (AKI).
Clinical Consequence: Loss of blood pressure reduction, fluid retention, or acute renal hemodynamic compromise.
Physician Precaution: Consult your physician before taking OTC pain relievers. Acetaminophen may be preferred for occasional pain depending on liver status.
Dietary Supplements, Herbs & Minerals (DNI)
Interactions with over-the-counter vitamins, minerals, and herbal preparationsNo acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.
Chronotherapy & Meal Administration Protocols
Optimal absorption, meal-timing rules & GI tolerability protocolsFrequently Researched Drug-Substance Combinations
Explore pairwise interaction dossiers and laboratory safety analysesMulti-Substance Interactive Radar
Taking Phenylephrine alongside daily coffee, supplements, or other medications?
Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.
Authoritative Clinical Evidence & Regulatory Sources
Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.